base 2 is a positional numeral system with two as its base. It uses 2 different digits for representing numbers. The digits for base 2 could be 0, and 1.

base 22 is a positional numeral system with twenty-two as its base. It uses 22 different digits for representing numbers. The digits for base 22 could be 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, a, b, c, d, e, f, g, h, i, j, k, and l.